

| 货号 | HC587014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 种属反应性 | Human, Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human COX17 (Lys21-Ile63). | ||||||||
| 靶标 | Cytochrome c oxidase copper chaperone, COX17 | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q14061 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Cytochrome c oxidase copper chaperone (COX17) is a ~6 kDa protein. Copper metallochaperone involved in the assembly of cytochrome c oxidase (respiratory chain complex IV, CIV). Binds two copper ions and delivers them to metallochaperones SCO1 and SCO2, which co-chaperone the copper ions to the Cu(A) site on the cytochrome c oxidase subunit II (MT-CO2/COX2), and to metallochaperone COX11 which relays the copper to the Cu(B) site on the cytochrome c oxidase subunit I (MT-CO1/COX1). 1. Leary, SC. et al. (2004) Human molecular genetics 13, 1839-48. PMID: 15229189 2. Oswald, C. et al. (2009) Journal of molecular biology 389, 470-9. PMID: 19393246 3. Vanišová, M. et al. (2019) Folia biologica 65, 181-187. PMID: 31903891 4. Nývltová, E. et al. (2022) Nature communications 13, 3615. PMID: 35750769 | ||||||||
| Note | For research use only. |

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