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Anti-Human ZFYVE27 Polyclonal Antibody (HP941014)

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概述
货号HP941014
品牌abinScience
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human ZFYVE27 (Lys361-Lys411).
靶标Spastic paraplegia 33 protein, SPG33, ZFYVE27, Protrudin, Zinc finger FYVE domain-containing protein 27
纯化方式Purified by antigen affinity column.
Accession号Q5T4F4
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Protrudin (ZFYVE27) is a ~45 kDa protein. Key regulator of RAB11-dependent vesicular trafficking during neurite extension through polarized membrane transport. Promotes axonal elongation and contributes to the establishment of neuronal cell polarity. Involved in nerve growth factor-induced neurite formation in VAPA-dependent manner. Contributes to both the formation and stabilization of the tubular ER network. Involved in ER morphogenesis by regulating the sheet-to-tubule balance and possibly the density of tubule interconnections.

1. Shirane, M. et al. (2006) Science (New York, N.Y.) 314, 818-21. PMID: 17082457
2. Saita, S. et al. (2009) The Journal of biological chemistry 284, 13766-13777. PMID: 19289470
3. Hashimoto, Y. et al. (2014) The Journal of biological chemistry 289, 12946-61. PMID: 24668814
4. Chang, J. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, 14954-9. PMID: 23969831
5. Matsuzaki, F. et al. (2011) Molecular biology of the cell 22, 4602-20. PMID: 21976701
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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