Anti-Human SPAG5 Polyclonal Antibody (HP190014)

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规格：

50ug
100ug

数量：

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概述
图片
参考文献
产品说明书

HP190014

abinScience

种属反应性

Human

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human SPAG5 (Met976-Asp1098).

Sperm-associated antigen 5, SPAG5, Astrin, Deepest, MAP126, Mitotic spindle-associated protein p126

Purified by antigen affinity column.

Accession号

Q96R06

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Sperm-associated antigen 5 (SPAG5) is a ~134 kDa protein. Essential component of the mitotic spindle required for normal chromosome segregation and progression into anaphase. Required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. In complex with SKAP, promotes stable microtubule-kinetochore attachments. May contribute to the regulation of separase activity. May regulate AURKA localization to mitotic spindle, but not to centrosomes and CCNB1 localization to both mitotic spindle and centrosomes.

1. Mack, GJ. et al. (2001) Proceedings of the National Academy of Sciences of the United States of America 98, 14434-9. PMID: 11724960

2. Gruber, J. et al. (2002) Journal of cell science 115, 4053-9. PMID: 12356910

3. Chu, X. et al. (2016) The Journal of biological chemistry 291, 20055-67. PMID: 27462074

4. Thein, KH. et al. (2007) The Journal of cell biology 178, 345-54. PMID: 17664331

5. Du, J. et al. (2008) Biochemical and biophysical research communications 370, 213-9. PMID: 18361916

6. Dunsch, AK. et al. (2011) The Journal of cell biology 192, 959-68. PMID: 21402792

7. Kodani, A. et al. (2015) eLife 4. PMID: 26297806

8. Thedieck, K. et al. (2013) Cell 154, 859-74. PMID: 23953116

9. Cheng, TS. et al. (2008) The Journal of biological chemistry 283, 2454-64. PMID: 18055457

For research use only.

产品说明书

Anti-Human SPAG5 Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human SPAG5 Polyclonal Antibody (HP190014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human SPAG5 Polyclonal Antibody (HP190014)

概述

图片

参考文献

产品说明书

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