Anti-Human USP2 Polyclonal Antibody (HF546014)

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100ug

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HF546014

abinScience

种属反应性

Human, Mouse, Rat

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human USP2 (Thr275-Met605).

Ubiquitin thioesterase 2, 41 kDa ubiquitin-specific protease, UBP41, Ubiquitin carboxyl-terminal hydrolase 2, Deubiquitinating enzyme 2, USP2, Ubiquitin-specific-processing protease 2

Purified by antigen affinity column.

Accession号

O75604

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Ubiquitin carboxyl-terminal hydrolase 2 (USP2) is a ~68 kDa protein. Hydrolase that deubiquitinates polyubiquitinated target proteins such as MDM2, MDM4 and CCND1. Isoform 1 and isoform 4 possess both ubiquitin-specific peptidase and isopeptidase activities. Deubiquitinates MDM2 without reversing MDM2-mediated p53/TP53 ubiquitination and thus indirectly promotes p53/TP53 degradation and limits p53 activity. Has no deubiquitinase activity against p53/TP53. Prevents MDM2-mediated degradation of MDM4.

1. Stevenson, LF. et al. (2007) The EMBO journal 26, 976-86. PMID: 17290220

2. Allende-Vega, N. et al. (2010) Oncogene 29, 432-41. PMID: 19838211

3. Shan, J. et al. (2009) Molecular cell 36, 469-76. PMID: 19917254

For research use only.

Western blot

Western blot analysis was performed using anti-USP2 polyclonal antibody at 1μg/ml on various samples.
Lane 1: NIH3T3 cell lysate

产品说明书

Anti-Human USP2 Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

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实验相关试剂

Anti-Human USP2 Polyclonal Antibody (HF546014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human USP2 Polyclonal Antibody (HF546014)

概述

图片

参考文献

产品说明书

相关产品推荐

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