

| 货号 | HT402014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human HAX1 (Lys205-Asp246). | ||||||||
| 靶标 | HS1BP1, HS1-binding protein 1, HAX1, HSP1BP-1, HCLS1-associated protein X-1, HS1-associating protein X-1, HAX-1 | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | O00165 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | HCLS1-associated protein X-1 (HAX1) is a ~31 kDa protein. Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. 1. Zhang, Y. et al. (2016) Cell 165, 434-448. PMID: 26997484 | ||||||||
| Note | For research use only. |

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