Anti-Human CIAO2B Polyclonal Antibody (HP061014)

价格:

规格：

50ug
100ug

数量：

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概述
图片
参考文献
产品说明书

HP061014

abinScience

种属反应性

Human, Mouse

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human CIAO2B (Thr29-Ser163).

Mitotic spindle-associated MMXD complex subunit MIP18, FAM96B, Protein FAM96B, MSS19-interacting protein of 18 kDa, CIAB, CIAO2B, MIP18, Cytosolic iron-sulfur assembly component 2B

Purified by antigen affinity column.

Accession号

Q9Y3D0

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Cytosolic iron-sulfur assembly component 2B (CIAO2B) is a ~17 kDa protein. Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. As a CIA complex component and in collaboration with CIAO1 and MMS19, binds to and facilitates the assembly of most cytosolic-nuclear Fe/S proteins. As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD. Together with MMS19, facilitates the transfer of Fe-S clusters to the motor protein KIF4A, which ensures proper localization of KIF4A to mitotic machinery components to promote the progression of mitosis.

1. Gari, K. et al. (2012) Science (New York, N.Y.) 337, 243-5. PMID: 22678361

2. Stehling, O. et al. (2012) Science (New York, N.Y.) 337, 195-9. PMID: 22678362

3. Stehling, O. et al. (2013) Cell metabolism 18, 187-98. PMID: 23891004

4. Ben-Shimon, L. et al. (2018) Journal of cell science 131. PMID: 29848660

5. Ito, S. et al. (2010) Molecular cell 39, 632-40. PMID: 20797633

For research use only.

产品说明书

Anti-Human CIAO2B Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human CIAO2B Polyclonal Antibody (HP061014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human CIAO2B Polyclonal Antibody (HP061014)

概述

图片

参考文献

产品说明书

相关产品推荐

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