

| 货号 | HX936014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 种属反应性 | Human, Mouse, Rat | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human RPL23A (Lys70-Ile156). | ||||||||
| 靶标 | Large ribosomal subunit protein uL23, RPL23A, 60S ribosomal protein L23a | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P62750 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Large ribosomal subunit protein uL23 (RPL23A) is a ~17 kDa protein. Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Binds a specific region on the 26S rRNA. May promote p53/TP53 degradation possibly through the stimulation of MDM2-mediated TP53 polyubiquitination. 1. Anger, AM. et al. (2013) Nature 497, 80-5. PMID: 23636399 2. Liang, X. et al. (2020) Nature communications 11, 3542. PMID: 32669547 3. Datta, D. et al. (2015) The Journal of biological chemistry 290, 21536-52. PMID: 26203195 | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-RPL23A polyclonal antibody at 1ug/mL on various samples.
Lane 1: 293T cell lysate
Lane 2: Jurkat cell lysate
Lane 3: U87 cell lysate
Lane 4: Mouse brain lysate
Lane 5: Mouse lung lysate
Lane 6: Mouse liver lysate
Lane 7: Rat brain lysate
Lane 8: Rat lung lysate
Lane 9: Rat liver lysate



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