

| 货号 | HC529014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 种属反应性 | Human, Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human GLO1 (Gln33-Met184). | ||||||||
| 靶标 | Glyoxalase I, Glx I, Ketone-aldehyde mutase, GLO1, Lactoylglutathione lyase, Methylglyoxalase, S-D-lactoylglutathione methylglyoxal lyase, Aldoketomutase | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q04760 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Lactoylglutathione lyase (GLO1) is a ~20 kDa protein. Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. Involved in the regulation of TNF-induced transcriptional activity of NF-kappa-B. Required for normal osteoclastogenesis. 1. Birkenmeier, G. et al. (2010) PloS one 5, e10399. PMID: 20454679 2. Chiba, T. et al. (2012) Bioorganic & medicinal chemistry letters 22, 7486-9. PMID: 23122816 3. Ridderström, M. et al. (1998) The Journal of biological chemistry 273, 21623-8. PMID: 9705294 4. de Hemptinne, V. et al. (2009) Molecular and cellular biochemistry 325, 169-78. PMID: 19199007 | ||||||||
| Note | For research use only. |

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