Anti-Human TRIM15 Polyclonal Antibody (HP976014)

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50ug
100ug

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概述
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参考文献
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HP976014

abinScience

种属反应性

Human

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human TRIM15 (Glu80-Pro275).

ZNF178, Tripartite motif-containing protein 15, TRIM15, ZNFB7, Zinc finger protein 178, RNF93, RING finger protein 93, Zinc finger protein B7

Purified by antigen affinity column.

Accession号

Q9C019

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

E3 ubiquitin-protein ligase TRIM15 is a ~52 kDa protein. E3 ubiquitin ligase that plays a role in several processes including innate antiviral immnity, cell migration and chemotaxis. Acts as a 'Lys-63'-specific ubiquitin ligase for MAPK1/ERK2 and MAPK3/ERK1, promoting their activation by facilitating their interaction with MAP2K1 and MAP2K2. Also plays a role in cell migration and chemotaxis by acting as a stable focal adhesion component upon recruitment by multi-adapter protein paxillin/PXN. Functions in the RIGI-mediated interferon induction pathway upstream or at the level of MAVS. Inhibits NF-kappa-B activation by turnover of 'Lys-63'-linked ubiquitination of MAP3K7/TAK1.

1. Uchil, PD. et al. (2013) Journal of virology 87, 257-72. PMID: 23077300

2. Zhang, J. et al. (2021) Journal of molecular histology 52, 839-848. PMID: 34142270

3. Zhu, G. et al. (2021) Nature cell biology 23, 978-991. PMID: 34497368

4. Uchil, PD. et al. (2014) Journal of cell science 127, 3928-42. PMID: 25015296

5. Roy, M. et al. (2022) Cellular signalling 91, 110210. PMID: 34871740

For research use only.

产品说明书

Anti-Human TRIM15 Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human TRIM15 Polyclonal Antibody (HP976014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human TRIM15 Polyclonal Antibody (HP976014)

概述

图片

参考文献

产品说明书

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