

| 货号 | HP758014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human MAP1LC3C (Arg11-Leu147). | ||||||||
| 靶标 | Microtubule-associated proteins 1A/1B light chain 3C, MAP1A/MAP1B LC3 C, Autophagy-related ubiquitin-like modifier LC3 C, MAP1A/MAP1B light chain 3 C, Microtubule-associated protein 1 light chain 3 gamma, MAP1 light chain 3-like protein 3, MAP1LC3C, Autophagy-related protein LC3 C | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q9BXW4 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Microtubule-associated protein 1 light chain 3 gamma (MAP1LC3C) is a ~16 kDa protein. Ubiquitin-like modifier that plays a crucial role in antibacterial autophagy (xenophagy) through the selective binding of CALCOCO2. Recruits all ATG8 family members to infecting bacteria such as S.typhimurium. May also play a role in aggrephagy, the macroautophagic degradation of ubiquitinated and aggregated proteins. 1. von Muhlinen, N. et al. (2012) Molecular cell 48, 329-42. PMID: 23022382 2. Liu, X. et al. (2017) The Journal of cell biology 216, 1301-1320. PMID: 28404643 | ||||||||
| Note | For research use only. |

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