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Anti-Human CTNND1 Polyclonal Antibody (HT249014)

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概述
货号HT249014
品牌abinScience
种属反应性Human, Mouse
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human CTNND1 (Glu367-Gln601).
靶标CTNND1, p120 catenin, Cadherin-associated Src substrate, CAS, Catenin delta-1, p120(ctn), KIAA0384, p120(cas)
纯化方式Purified by antigen affinity column.
Accession号O60716
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Catenin delta-1 (CTNND1) is a ~108 kDa protein. Key regulator of cell-cell adhesion that associates with and regulates the cell adhesion properties of both C-, E- and N-cadherins, being critical for their surface stability. Promotes localization and retention of DSG3 at cell-cell junctions, via its interaction with DSG3. Beside cell-cell adhesion, regulates gene transcription through several transcription factors including ZBTB33/Kaiso2 and GLIS2, and the activity of Rho family GTPases and downstream cytoskeletal dynamics. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors.

1. Davis, MA. et al. (2003) The Journal of cell biology 163, 525-34. PMID: 14610055
2. Ishiyama, N. et al. (2010) Cell 141, 117-28. PMID: 20371349
3. Kanno, M. et al. (2008) Experimental cell research 314, 1683-92. PMID: 18343367
4. Daniel, JM. et al. (1999) Molecular and cellular biology 19, 3614-23. PMID: 10207085
5. Hosking, CR. et al. (2007) Molecular biology of the cell 18, 1918-27. PMID: 17344476
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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