

| 货号 | HP038014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 种属反应性 | Human, Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human PPP1R13L (Asn626-Gly816). | ||||||||
| 靶标 | IASPP, Inhibitor of ASPP protein, NKIP1, RAI, NFkB-interacting protein 1, PPP1R13BL, RelA-associated inhibitor, Protein iASPP, PPP1R13L, PPP1R13B-like protein | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q8WUF5 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | RelA-associated inhibitor (PPP1R13L) is a ~89 kDa protein. Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis. Is involved in NF-kappa-B dependent negative regulation of inflammatory response. 1. Bergamaschi, D. et al. (2003) Nature genetics 33, 162-7. PMID: 12524540 2. Falik-Zaccai, TC. et al. (2017) EMBO molecular medicine 9, 319-336. PMID: 28069640 | ||||||||
| Note | For research use only. |

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