Anti-Human WASL Polyclonal Antibody (HT262014)

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规格：

50ug
100ug

数量：

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参考文献
产品说明书

HT262014

abinScience

种属反应性

Human, Mouse, Rat

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human WASL (Leu21-Arg148).

N-WASP, WASL, Neural Wiskott-Aldrich syndrome protein

Purified by antigen affinity column.

Accession号

O00401

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Actin nucleation-promoting factor WASL is a ~54 kDa protein. Regulates actin polymerization by stimulating the actin-nucleating activity of the Arp2/3 complex. Involved in various processes, such as mitosis and cytokinesis, via its role in the regulation of actin polymerization. Together with CDC42, involved in the extension and maintenance of the formation of thin, actin-rich surface projections called filopodia. In addition to its role in the cytoplasm, also plays a role in the nucleus by regulating gene transcription, probably by promoting nuclear actin polymerization. Binds to HSF1/HSTF1 and forms a complex on heat shock promoter elements (HSE) that negatively regulates HSP90 expression.

1. Wu, X. et al. (2006) Nature cell biology 8, 756-63. PMID: 16767080

2. Vingadassalom, D. et al. (2009) Proceedings of the National Academy of Sciences of the United States of America 106, 6754-9. PMID: 19366662

3. Zhang, J. et al. (2009) The Journal of biological chemistry 284, 21659-69. PMID: 19487689

4. Gaucher, JF. et al. (2012) The Journal of biological chemistry 287, 34646-59. PMID: 22847007

5. Aitio, O. et al. (2012) Structure (London, England : 1993) 20, 1692-703. PMID: 22921828

6. Miki, H. et al. (1998) Nature 391, 93-6. PMID: 9422512

7. Rajabian, T. et al. (2009) Nature cell biology 11, 1212-8. PMID: 19767742

For research use only.

产品说明书

Anti-Human WASL Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human WASL Polyclonal Antibody (HT262014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human WASL Polyclonal Antibody (HT262014)

概述

图片

参考文献

产品说明书

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