Anti-Human RBM15B Polyclonal Antibody (HP636014)

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规格：

50ug
100ug

数量：

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概述
图片
参考文献
产品说明书

HP636014

abinScience

种属反应性

Human, Mouse

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human RBM15B (Asn710-Ala890).

HuOTT3, RBM15B, One-twenty two protein 3, OTT3, RNA-binding motif protein 15B, HsOTT3, Putative RNA-binding protein 15B

Purified by antigen affinity column.

Accession号

Q8NDT2

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Putative RNA-binding protein 15B (RBM15B) is a ~97 kDa protein. RNA-binding protein that acts as a key regulator of N6-methyladenosine (m6A) methylation of RNAs, thereby regulating different processes, such as alternative splicing of mRNAs and X chromosome inactivation mediated by Xist RNA. Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing. Plays a key role in m6A methylation, possibly by binding target RNAs and recruiting the WMM complex. Involved in random X inactivation mediated by Xist RNA: acts by binding Xist RNA and recruiting the WMM complex, which mediates m6A methylation, leading to target YTHDC1 reader on Xist RNA and promoting transcription repression activity of Xist. Functions in the regulation of alternative or illicit splicing, possibly by regulating m6A methylation.

1. Hiriart, E. et al. (2005) The Journal of biological chemistry 280, 36935-45. PMID: 16129689

2. Patil, DP. et al. (2016) Nature 537, 369-373. PMID: 27602518

3. Loyer, P. et al. (2011) The Journal of biological chemistry 286, 147-59. PMID: 21044963

4. Uranishi, H. et al. (2009) The Journal of biological chemistry 284, 26106-16. PMID: 19586903

For research use only.

产品说明书

Anti-Human RBM15B Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human RBM15B Polyclonal Antibody (HP636014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human RBM15B Polyclonal Antibody (HP636014)

概述

图片

参考文献

产品说明书

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