Anti-Human SUFU Polyclonal Antibody (HP131014)

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规格：

50ug
100ug

数量：

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概述
图片
参考文献
产品说明书

HP131014

abinScience

种属反应性

Human, Mouse

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human SUFU (Gly33-Asn265).

SUFU, Suppressor of fused homolog, SUFUH

Purified by antigen affinity column.

Accession号

Q9UMX1

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Suppressor of fused homolog (SUFU) is a ~53 kDa protein. Negative regulator in the hedgehog/smoothened signaling pathway. Down-regulates GLI1-mediated transactivation of target genes. Down-regulates GLI2-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome.

1. Kogerman, P. et al. (1999) Nature cell biology 1, 312-9. PMID: 10559945

2. Stone, DM. et al. (1999) Journal of cell science 112 ( Pt 23), 4437-48. PMID: 10564661

3. Murone, M. et al. (2000) Nature cell biology 2, 310-2. PMID: 10806483

4. Taylor, MD. et al. (2002) Nature genetics 31, 306-10. PMID: 12068298

5. Clark, HF. et al. (2003) Genome research 13, 2265-70. PMID: 12975309

6. Merchant, M. et al. (2004) Molecular and cellular biology 24, 8627-41. PMID: 15367681

7. Chi, S. et al. (2012) Cellular signalling 24, 1222-8. PMID: 22365972

8. Zhang, Y. et al. (2013) Nature communications 4, 2608. PMID: 24217340

9. Cherry, AL. et al. (2013) Acta crystallographica. Section D, Biological crystallography 69, 2563-79. PMID: 24311597

10. Raducu, M. et al. (2016) The EMBO journal 35, 1400-16. PMID: 27234298

For research use only.

产品说明书

Anti-Human SUFU Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human SUFU Polyclonal Antibody (HP131014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human SUFU Polyclonal Antibody (HP131014)

概述

图片

参考文献

产品说明书

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