Anti-Human MECR Polyclonal Antibody (HP611014)

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规格：

50ug
100ug

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概述
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参考文献
产品说明书

HP611014

abinScience

种属反应性

Human

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human MECR (Arg42-Met373).

MECR, NRBF-1, Nuclear receptor-binding factor 1, NBRF1, 2-enoyl thioester reductase, HsNrbf-1, Enoyl-[acyl-carrier-protein] reductase, mitochondrial

Purified by antigen affinity column.

Accession号

Q9BV79

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Enoyl-[acyl-carrier-protein] reductase, mitochondrial (MECR) is a ~40 kDa protein. Catalyzes the NADPH-dependent reduction of trans-2-enoyl thioesters in mitochondrial fatty acid synthesis (fatty acid synthesis type II). Fatty acid chain elongation in mitochondria uses acyl carrier protein (ACP) as an acyl group carrier, but the enzyme accepts both ACP and CoA thioesters as substrates in vitro. Displays a preference for medium-chain over short- and long-chain substrates. May provide the octanoyl chain used for lipoic acid biosynthesis, regulating protein lipoylation and mitochondrial respiratory activity particularly in Purkinje cells. Involved in iron homeostasis; affecting Fe-S cluster assembly and ceramide metabolism.

1. Miinalainen, IJ. et al. (2003) The Journal of biological chemistry 278, 20154-61. PMID: 12654921

2. Chen, ZJ. et al. (2008) Journal of molecular biology 379, 830-44. PMID: 18479707

3. Heimer, G. et al. (2016) American journal of human genetics 99, 1229-1244. PMID: 27817865

4. Dutta, D. et al. (2023) Nature metabolism 5, 1595-1614. PMID: 37653044

For research use only.

产品说明书

Anti-Human MECR Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human MECR Polyclonal Antibody (HP611014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human MECR Polyclonal Antibody (HP611014)

概述

图片

参考文献

产品说明书

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