Anti-Human ZFP36L1 Polyclonal Antibody (HC370014)

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规格：

50ug
100ug

数量：

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参考文献
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HC370014

abinScience

种属反应性

Human, Mouse, Rat

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human ZFP36L1 (Arg121-Arg195).

ERF-1, ZFP36-like 1, TIS11B, BRF1, ZFP36L1, Butyrate response factor 1, Zinc finger protein 36, C3H1 type-like 1, ERF1, RNF162B, BERG36, TPA-induced sequence 11b, mRNA decay activator protein ZFP36L1, EGF-response factor 1

Purified by antigen affinity column.

Accession号

Q07352

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

mRNA decay activator protein ZFP36L1 is a ~36 kDa protein. Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Also induces the degradation of ARE-containing mRNAs even in absence of poly(A) tail. Binds to 3'-UTR ARE of numerous mRNAs.

1. Stoecklin, G. et al. (2002) The EMBO journal 21, 4709-18. PMID: 12198173

2. Ciais, D. et al. (2004) Oncogene 23, 8673-80. PMID: 15467755

3. Schmidlin, M. et al. (2004) The EMBO journal 23, 4760-9. PMID: 15538381

4. Benjamin, D. et al. (2006) Molecular and cellular biology 26, 9497-507. PMID: 17030608

5. Duan, H. et al. (2009) Molecular endocrinology (Baltimore, Md.) 23, 497-509. PMID: 19179481

6. Vignudelli, T. et al. (2010) Molecular biology of the cell 21, 3340-51. PMID: 20702587

7. Viengchareun, S. et al. (2014) Journal of the American Society of Nephrology : JASN 25, 2213-21. PMID: 24700863

8. Zekavati, A. et al. (2014) PloS one 9, e102625. PMID: 25014217

9. Adachi, S. et al. (2014) Nucleic acids research 42, 10037-49. PMID: 25106868

10. Chen, MT. et al. (2015) Scientific reports 5, 16229. PMID: 26542173

For research use only.

产品说明书

Anti-Human ZFP36L1 Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

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试剂盒

实验相关试剂

Anti-Human ZFP36L1 Polyclonal Antibody (HC370014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human ZFP36L1 Polyclonal Antibody (HC370014)

概述

图片

参考文献

产品说明书

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