

| 货号 | HS799014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 种属反应性 | Human, Mouse, Rat | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human PTGES3/P23 (Met1-Glu160). | ||||||||
| 靶标 | PTGES3, Hsp90 co-chaperone, P23, Progesterone receptor complex p23, Prostaglandin E synthase 3, cPGES, Telomerase-binding protein p23, Cytosolic prostaglandin E2 synthase, TEBP | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q15185 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
||||||||
| 产品使用信息 |
| ||||||||
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Prostaglandin E synthase 3 (PTGES3/P23) is a ~18 kDa protein. Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway. 1. Tanioka, T. et al. (2000) The Journal of biological chemistry 275, 32775-82. PMID: 10922363 2. Forsythe, HL. et al. (2001) The Journal of biological chemistry 276, 15571-4. PMID: 11274138 3. Freeman, BC. et al. (2002) Science (New York, N.Y.) 296, 2232-5. PMID: 12077419 4. Song, D. et al. (2014) The Journal of biological chemistry 289, 14656-65. PMID: 24711448 | ||||||||
| Note | For research use only. |

Lane 1: A549 cell lysate
Lane 2: PC-3 cell lysate
Lane 3: Hela cell lysate
Lane 4: HepG2 cell lysate
Lane 5: NIH3T3 cell lysate
Lane 6: 293T cell lysate
Lane 7: Mouse testis lysate
Lane 8: Mouse brain lysate
Lane 9: Mouse spleen lysate
Lane 10: Rat testis lysate
Lane11: Rat brain lysate



24小时产品查询

扫一扫关注我们

专属渠道经理