首页 > 产品中心 > 抗体 > 一抗

Anti-Human CNP Polyclonal Antibody (HY072014)

价格:
规格:
  • 50ug
  • 100ug
数量:
  • 概述

  • 图片

  • 参考文献

  • 产品说明书

概述
货号HY072014
品牌abinScience
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human CNP (Glu40-Gly396).
靶标CNPase, 2', 3'-cyclic-nucleotide 3'-phosphodiesterase, CNP
纯化方式Purified by antigen affinity column.
Accession号P09543
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

2',3'-cyclic-nucleotide 3'-phosphodiesterase (CNP) is a ~47 kDa protein. Myelin-associated enzyme that catalyzes the phosphodiester hydrolysis of 2',3'-cyclic nucleotides to 2'-nucleotides. In the mitochondria, regulates the functioning of the mitochondrial permeability transition pore (mPTP), and thus is involved in the mechanisms of cell death, both apoptosis and necrosis. Acts as an antiviral factor by suppressing the assembly of SARS-CoV-2 virions.

1. Logue, J. et al. (2023) PLoS pathogens 19, e1011870. PMID: 38117830
NoteFor research use only.
图片
  • Western blot

    Western blot analysis was performed using anti-CNP polyclonal antibody at 1μg/ml on various samples.
    Lane 1: HepG2 cell lysate
    Lane 2: U251 cell lysate
    Lane 3: Hela cell lysate
    Lane 4: Mouse brain lysate
    Lane 5: Mouse cerebellum lysate
    Lane 6: Rat brain lysate
    Lane 7: Rat cerebellum lysate

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

相关产品推荐