首页 > 产品中心 > 抗体 > 一抗

Anti-Human RBM24 Polyclonal Antibody (HP302014)

价格:
规格:
  • 50ug
  • 100ug
数量:
  • 概述

  • 图片

  • 参考文献

  • 产品说明书

概述
货号HP302014
品牌abinScience
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human RBM24 (Thr11-Lys91).
靶标RNA-binding region-containing protein 6, RNA-binding protein 24, RNA-binding motif protein 24, RBM24, RNPC6
纯化方式Purified by antigen affinity column.
Accession号Q9BX46
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

RNA-binding protein 24 (RBM24) is a ~24 kDa protein. Multifunctional RNA-binding protein involved in the regulation of pre-mRNA splicing, mRNA stability and mRNA translation important for cell fate decision and differentiation. Plays a major role in pre-mRNA alternative splicing regulation. Mediates preferentially muscle-specific exon inclusion in numerous mRNAs important for striated cardiac and skeletal muscle cell differentiation. Binds to intronic splicing enhancer (ISE) composed of stretches of GU-rich motifs localized in flanking intron of exon that will be included by alternative splicing. Involved in embryonic stem cell (ESC) transition to cardiac cell differentiation by promoting pre-mRNA alternative splicing events of several pluripotency and/or differentiation genes.

1. Jin, D. et al. (2010) Genes to cells : devoted to molecular & cellular mechanisms 15, 1158-67. PMID: 20977548
2. Xu, E. et al. (2014) Molecular cancer research : MCR 12, 359-69. PMID: 24375645
3. Lin, Y. et al. (2018) The international journal of biochemistry & cell biology 94, 10-21. PMID: 29104163
4. Zhang, M. et al. (2018) Cell death and differentiation 25, 1118-1130. PMID: 29358667
5. Zhang, T. et al. (2016) Stem cells (Dayton, Ohio) 34, 1776-89. PMID: 26990106
6. Jiang, Y. et al. (2014) The Journal of biological chemistry 289, 3164-75. PMID: 24356969
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

相关产品推荐