

| 货号 | HP251014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human STEAP3 (Lys30-Arg207). | ||||||||
| 靶标 | hpHyde, STEAP3, pHyde, Tumor suppressor-activated pathway protein 6, TSAP6, Metalloreductase STEAP3, Six-transmembrane epithelial antigen of prostate 3, hTSAP6, Dudulin-2 | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q658P3 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Metalloreductase STEAP3 is a ~54 kDa protein. Integral membrane protein that functions as a NADPH-dependent ferric-chelate reductase, using NADPH from one side of the membrane to reduce a Fe(3+) chelate that is bound on the other side of the membrane. Mediates sequential transmembrane electron transfer from NADPH to FAD and onto heme, and finally to the Fe(3+) chelate. Can also reduce Cu(2+) to Cu(1+). Mediates efficient transferrin-dependent iron uptake in erythroid cells. May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. 1. Kleven, MD. et al. (2015) The Journal of biological chemistry 290, 22558-69. PMID: 26205815 2. Amzallag, N. et al. (2004) The Journal of biological chemistry 279, 46104-12. PMID: 15319436 3. Yu, X. et al. (2006) Cancer research 66, 4795-801. PMID: 16651434 | ||||||||
| Note | For research use only. |

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