Anti-Human ABHD2 Polyclonal Antibody (HY050014)

价格:

规格：

50ug
100ug

数量：

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概述
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参考文献
产品说明书

HY050014

abinScience

种属反应性

Human, Mouse

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human ABHD2 (Ala40-Glu425).

Monoacylglycerol lipase ABHD2, ABHD2, LABH2, Protein PHPS1-2, 2-arachidonoylglycerol hydrolase, Abhydrolase domain-containing protein 2, Acetylesterase, Lung alpha/beta hydrolase 2, Progesterone-sensitive lipase

Purified by antigen affinity column.

Accession号

P08910

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Monoacylglycerol lipase ABHD2 is a ~48 kDa protein. Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1-arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2AG, an inhibitor of the sperm calcium channel CatSper, leading to calcium influx via CatSper and sperm activation. May also play a role in smooth muscle cells migration.

1. Miller, MR. et al. (2016) Science (New York, N.Y.) 352, 555-9. PMID: 26989199

2. M, NK. et al. (2016) Bioscience reports 36. PMID: 27247428

For research use only.

Western blot

Western blot analysis was performed using anti-ABHD2 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse heart lysate
Lane 2: Mouse lung lysate
Lane 3: Rat heart lysate

产品说明书

Anti-Human ABHD2 Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

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试剂盒

实验相关试剂

Anti-Human ABHD2 Polyclonal Antibody (HY050014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human ABHD2 Polyclonal Antibody (HY050014)

概述

图片

参考文献

产品说明书

相关产品推荐

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