Anti-Human COMMD5 Polyclonal Antibody (HP513014)

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50ug
100ug

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概述
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参考文献
产品说明书

HP513014

abinScience

种属反应性

Human

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human COMMD5 (Glu32-Asp224).

COMM domain-containing protein 5, Hypertension-related calcium-regulated gene protein, HCaRG, COMMD5

Purified by antigen affinity column.

Accession号

Q9GZQ3

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

COMM domain-containing protein 5 (COMMD5) is a ~24 kDa protein. Scaffold protein in the commander complex that is essential for endosomal recycling of transmembrane cargos; the commander complex is composed of the CCC subcomplex and the retriever subcomplex. May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. Negatively regulates cell proliferation. Negatively regulates cell cycle G2/M phase transition probably by transactivating p21/CDKN1A through the p53/TP53-independent signaling pathway. Involved in kidney proximal tubule morphogenesis.

1. Healy, MD. et al. (2023) Cell 186, 2219-2237.e29. PMID: 37172566

2. Laulumaa, S. et al. (2024) Nature structural & molecular biology 31, 925-938. PMID: 38459129

3. Mao, X. et al. (2011) The Journal of biological chemistry 286, 32355-65. PMID: 21778237

4. Burstein, E. et al. (2005) The Journal of biological chemistry 280, 22222-32. PMID: 15799966

For research use only.

产品说明书

Anti-Human COMMD5 Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human COMMD5 Polyclonal Antibody (HP513014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human COMMD5 Polyclonal Antibody (HP513014)

概述

图片

参考文献

产品说明书

相关产品推荐

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