Anti-Human UBE2D3 Polyclonal Antibody (HX067014)

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规格：

50ug
100ug

数量：

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概述
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参考文献
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HX067014

abinScience

种属反应性

Human, Mouse, Rat

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human UBE2D3 (Met1-Met147).

Ubiquitin-conjugating enzyme E2-17 kDa 3, (E3-independent) E2 ubiquitin-conjugating enzyme D3, UBC5C, UBE2D3, Ubiquitin-conjugating enzyme E2(17)KB 3, Ubiquitin carrier protein D3, Ubiquitin-protein ligase D3, UBCH5C, Ubiquitin-conjugating enzyme E2 D3, E2 ubiquitin-conjugating enzyme D3

Purified by antigen affinity column.

Accession号

P61077

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Ubiquitin-conjugating enzyme E2 D3 (UBE2D3) is a ~16 kDa protein. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-, as well as 'Lys-48'-linked polyubiquitination. Cooperates with the E2 CDC34 and the SCF(FBXW11) E3 ligase complex for the polyubiquitination of NFKBIA leading to its subsequent proteasomal degradation. Acts as an initiator E2, priming the phosphorylated NFKBIA target at positions 'Lys-21' and/or 'Lys-22' with a monoubiquitin. Ubiquitin chain elongation is then performed by CDC34, building ubiquitin chains from the UBE2D3-primed NFKBIA-linked ubiquitin.

1. Rajendra, R. et al. (2004) The Journal of biological chemistry 279, 36440-4. PMID: 15247280

2. Huang, J. et al. (2004) The Journal of biological chemistry 279, 54110-6. PMID: 15496420

3. Kubori, T. et al. (2008) Molecular microbiology 67, 1307-19. PMID: 18284575

4. David, Y. et al. (2010) The Journal of biological chemistry 285, 8595-604. PMID: 20061386

5. Wenzel, DM. et al. (2011) Nature 474, 105-8. PMID: 21532592

6. Peng, H. et al. (2017) Cell research 27, 657-674. PMID: 28322253

7. Wu, K. et al. (2010) Molecular cell 37, 784-96. PMID: 20347421

8. Gonen, H. et al. (1999) The Journal of biological chemistry 274, 14823-30. PMID: 10329681

For research use only.

产品说明书

Anti-Human UBE2D3 Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

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Anti-Human UBE2D3 Polyclonal Antibody (HX067014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human UBE2D3 Polyclonal Antibody (HX067014)

概述

图片

参考文献

产品说明书

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