

| 货号 | HP067014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 种属反应性 | Human, Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human AEBP2 (Ser274-Ser358). | ||||||||
| 靶标 | Adipocyte enhancer-binding protein 2, Zinc finger protein AEBP2, AEBP2, AE-binding protein 2 | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q6ZN18 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Zinc finger protein AEBP2 is a ~54 kDa protein. Acts as an accessory subunit for the core Polycomb repressive complex 2 (PRC2), which mediates histone H3K27 (H3K27me3) trimethylation on chromatin leading to transcriptional repression of the affected target gene. Plays a role in nucleosome localization of the PRC2 complex. 1. Cao, R. et al. (2004) Molecular cell 15, 57-67. PMID: 15225548 2. Chen, S. et al. (2018) Molecular cell 69, 840-852.e5. PMID: 29499137 3. Chen, S. et al. (2020) Molecular cell 77, 1265-1278.e7. PMID: 31959557 | ||||||||
| Note | For research use only. |

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