Anti-E2F1/RBBP3 Polyclonal Antibody (HX082014)

价格:

规格：

50ug
100ug

数量：

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概述
图片
参考文献
产品说明书

HX082014

abinScience

种属反应性

Human

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human E2F1/RBBP3 (Val88-Phe437).

Retinoblastoma-binding protein 3, Retinoblastoma-associated protein 1, RBBP-3, Transcription factor E2F1, RBBP3, E2F1, E2F-1, RBAP-1, pRB-binding protein E2F-1, PBR3

Purified by antigen affinity column.

Accession号

Q01094

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Transcription factor E2F1 (RBBP3) is a ~46 kDa protein. Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis. Blocks adipocyte differentiation by binding to specific promoters repressing CEBPA binding to its target gene promoters.

1. Martínez-Balbás, MA. et al. (2000) The EMBO journal 19, 662-71. PMID: 10675335

2. Stevens, C. et al. (2003) Nature cell biology 5, 401-9. PMID: 12717439

3. García-Alvarez, G. et al. (2007) Biochimica et biophysica acta 1773, 375-82. PMID: 17050006

4. Wang, C. et al. (2007) The Journal of biological chemistry 282, 29902-9. PMID: 17704056

5. Wang, C. et al. (2008) FEBS letters 582, 2793-8. PMID: 18625225

6. Wang, D. et al. (2018) Journal of molecular cell biology 10, 60-73. PMID: 28992046

8. Zaragoza, K. et al. (2010) Molecular and cellular biology 30, 2293-304. PMID: 20176812

For research use only.

产品说明书

Anti-E2F1/RBBP3 Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-E2F1/RBBP3 Polyclonal Antibody (HX082014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-E2F1/RBBP3 Polyclonal Antibody (HX082014)

概述

图片

参考文献

产品说明书

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