Anti-Human TLR5 Polyclonal Antibody (HT266014)

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100ug

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HT266014

abinScience

种属反应性

Human

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human TLR5 (Ile21-Phe115).

TIL3, TLR5, Toll/interleukin-1 receptor-like protein 3, Toll-like receptor 5

Purified by antigen affinity column.

Accession号

O60602

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Toll-like receptor 5 (CD285/TLR5) is a ~97 kDa protein. Pattern recognition receptor (PRR) located on the cell surface that participates in the activation of innate immunity and inflammatory response. Recognizes small molecular motifs named pathogen-associated molecular pattern (PAMPs) expressed by pathogens and microbe-associated molecular patterns (MAMPs) usually expressed by resident microbiota. Upon ligand binding such as bacterial flagellins, recruits intracellular adapter proteins MYD88 and TRIF leading to NF-kappa-B activation, cytokine secretion and induction of the inflammatory response. Plays thereby an important role in the relationship between the intestinal epithelium and enteric microbes and contributes to the gut microbiota composition throughout life.

1. Hayashi, F. et al. (2001) Nature 410, 1099-103. PMID: 11323673

2. Blohmke, CJ. et al. (2008) Journal of immunology (Baltimore, Md. : 1950) 180, 7764-73. PMID: 18490781

3. Bielaszewska, M. et al. (2018) International journal of medical microbiology : IJMM 308, 882-889. PMID: 29934223

4. Gewirtz, AT. et al. (2001) Journal of immunology (Baltimore, Md. : 1950) 167, 1882-5. PMID: 11489966

5. Choi, YJ. et al. (2010) The Journal of biological chemistry 285, 37570-8. PMID: 20855887

For research use only.

产品说明书

Anti-Human TLR5 Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human TLR5 Polyclonal Antibody (HT266014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human TLR5 Polyclonal Antibody (HT266014)

概述

图片

参考文献

产品说明书

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