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Anti-Human LIPC Polyclonal Antibody (HY234014)

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规格:
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  • 100ug
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概述
货号HY234014
品牌abinScience
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human LIPC (Glu47-Pro478).
靶标Phospholipase A1, Lipase member C, LIPC, Hepatic lipase, Hepatic triacylglycerol lipase, Lysophospholipase, HTGL, HL
纯化方式Purified by antigen affinity column.
Accession号P11150
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Hepatic triacylglycerol lipase (LIPC) is a ~55 kDa protein. Catalyzes the hydrolysis of triglycerides and phospholipids present in circulating plasma lipoproteins, including chylomicrons, intermediate density lipoproteins (IDL), low density lipoproteins (LDL) of large size and high density lipoproteins (HDL), releasing free fatty acids (FFA) and smaller lipoprotein particles. Also exhibits lysophospholipase activity. Can hydrolyze both neutral lipid and phospholipid substrates but shows a greater binding affinity for neutral lipid substrates than phospholipid substrates. In native LDL, preferentially hydrolyzes the phosphatidylcholine species containing polyunsaturated fatty acids at sn-2 position.

1. McCoy, MG. et al. (2002) Journal of lipid research 43, 921-9. PMID: 12032167
2. Yang, P. et al. (2015) Biochimica et biophysica acta 1851, 1327-36. PMID: 26193433
3. Dugi, KA. et al. (1995) The Journal of biological chemistry 270, 25396-401. PMID: 7592706
4. Hill, JS. et al. (1996) The Journal of biological chemistry 271, 22931-6. PMID: 8798474
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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