Anti-BMP2 Polyclonal Antibody (HY576014)

价格:

规格：

50ug
100ug

数量：

一键复制产品信息

概述
图片
参考文献
产品说明书

HY576014

abinScience

种属反应性

Human, Mouse, Rat

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human BMP2 (Gln283-Arg396).

BMP-2, BMP2A, Bone morphogenetic protein 2A, Bone morphogenetic protein 2, BMP2, BMP-2A

Purified by antigen affinity column.

Accession号

P12643

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Bone morphogenetic protein 2 (BMP2) is a ~44 kDa protein. Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including cardiogenesis, neurogenesis, and osteogenesis. Induces cartilage and bone formation. Initiates the canonical BMP signaling cascade by associating with type I receptor BMPR1A and type II receptor BMPR2. Once all three components are bound together in a complex at the cell surface, BMPR2 phosphorylates and activates BMPR1A. In turn, BMPR1A propagates signal by phosphorylating SMAD1/5/8 that travel to the nucleus and act as activators and repressors of transcription of target genes.

1. Lavery, K. et al. (2008) The Journal of biological chemistry 283, 20948-58. PMID: 18436533

2. Tanaka, K. et al. (2014) Calcified tissue international 94, 454-64. PMID: 24362451

3. Seeherman, HJ. et al. (2019) Science translational medicine 11. PMID: 31019025

4. Wozney, JM. et al. (1988) Science (New York, N.Y.) 242, 1528-34. PMID: 3201241

5. Keller, S. et al. (2004) Nature structural & molecular biology 11, 481-8. PMID: 15064755

6. Weber, D. et al. (2007) BMC structural biology 7, 6. PMID: 17295905

7. Liu, F. et al. (1995) Molecular and cellular biology 15, 3479-86. PMID: 7791754

8. Wang, CY. et al. (2020) Blood 135, 453-456. PMID: 31800957

9. Tsukahara, S. et al. (2006) The Biochemical journal 398, 595-603. PMID: 16771708

For research use only.

产品说明书

Anti-BMP2 Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-BMP2 Polyclonal Antibody (HY576014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-BMP2 Polyclonal Antibody (HY576014)

概述

图片

参考文献

产品说明书

相关产品推荐

获取报价