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Anti-UXT Polyclonal Antibody (HV545014)

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概述
货号HV545014
品牌abinScience
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human UXT (Glu15-His157).
靶标ART-27, Protein UXT, Ubiquitously expressed transcript protein, Androgen receptor trapped clone 27 protein, UXT
纯化方式Purified by antigen affinity column.
Accession号Q9UBK9
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Protein UXT is a ~18 kDa protein. Involved in gene transcription regulation. Acts in concert with the corepressor URI1 to regulate androgen receptor AR-mediated transcription. Together with URI1, associates with chromatin to the NKX3-1 promoter region. Negatively regulates the transcriptional activity of the estrogen receptor ESR1 by inducing its translocation into the cytoplasm. May act as nuclear chaperone that facilitates the formation of the NF-kappa-B enhanceosome and thus positively regulates NF-kappa-B transcription activity.

1. Mita, P. et al. (2011) Molecular and cellular biology 31, 3639-52. PMID: 21730289
2. Sánchez-Morgan, N. et al. (2017) Journal of cellular biochemistry 118, 2347-2356. PMID: 28106301
3. Markus, SM. et al. (2002) Molecular biology of the cell 13, 670-82. PMID: 11854421
4. Sun, S. et al. (2007) The Journal of cell biology 178, 231-44. PMID: 17620405
5. Huang, Y. et al. (2011) Molecular biology of the cell 22, 1389-97. PMID: 21307340
6. Moss, TN. et al. (2007) In vitro cellular & developmental biology. Animal 43, 139-46. PMID: 17554592
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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