Anti-Human MDR1/ABCB1 Polyclonal Antibody (HY466014)

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50ug
100ug

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概述
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参考文献
产品说明书

HY466014

abinScience

种属反应性

Human

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human CD243/ABCB1 (Phe394-Val672).

Phospholipid transporter ABCB1, MDR1, CD243, ATP-binding cassette sub-family B member 1, ABCB1, Multidrug resistance protein 1, P-glycoprotein 1, ATP-dependent translocase ABCB1, PGY1

Purified by antigen affinity column.

Accession号

P08183

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

ATP-dependent translocase ABCB1 (CD243) is a ~141 kDa protein. Translocates drugs and phospholipids across the membrane. Catalyzes the flop of phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membrane. Participates mainly to the flop of phosphatidylcholine, phosphatidylethanolamine, beta-D-glucosylceramides and sphingomyelins. Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.

1. Choi, KH. et al. (1988) Cell 53, 519-29. PMID: 2897240

2. Masud, SN. et al. (2022) Nature chemical biology 18, 1370-1379. PMID: 35970996

3. van Helvoort, A. et al. (1996) Cell 87, 507-17. PMID: 8898203

4. Chen, G. et al. (1997) The Journal of biological chemistry 272, 5974-82. PMID: 9038218

5. Shafik, SH. et al. (2022) PLoS biology 20, e3001616. PMID: 35507548

For research use only.

产品说明书

Anti-Human MDR1/ABCB1 Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

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实验相关试剂

Anti-Human MDR1/ABCB1 Polyclonal Antibody (HY466014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human MDR1/ABCB1 Polyclonal Antibody (HY466014)

概述

图片

参考文献

产品说明书

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