| 货号 | HF626014 |
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| 品牌 | abinScience |
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| 种属反应性 | Human |
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| 应用 | ELISA, IHC, WB |
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| 宿主 | Rabbit |
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| 克隆类型 | Polyclonal |
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| 同种型 | IgG |
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| 免疫原 | E. coli - derived recombinant CD233/SLC4A1 (Ala35-Ser290). |
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| 靶标 | AE 1, AE1, Anion exchange protein 1, Anion exchanger 1, Band 3 anion transport protein, CD233, DI, EPB3, SLC4A1, Solute carrier family 4 member 1 |
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| 内毒素水平 | Please contact with the lab for this information. |
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| 纯化方式 | Purified by antigen affinity column. |
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| Accession号 | P02730 |
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| 状态 | Liquid |
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| 保存溶液 |
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
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| 重悬 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
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| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
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| 产品使用信息 |
| 应用方法 |
稀释比例 |
| ELISA |
1:5000-1:20000 |
| IHC |
1:50-1:500 |
| WB |
1:500-1:2000 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
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| 背景 | Band 3 anion transport protein (CD233/SLC4A1) is a ~101 kDa protein. Functions both as a transporter that mediates electroneutral anion exchange across the cell membrane and as a structural protein. Component of the ankyrin-1 complex of the erythrocyte membrane; required for normal flexibility and stability of the erythrocyte membrane and for normal erythrocyte shape via the interactions of its cytoplasmic domain with cytoskeletal proteins, glycolytic enzymes, and hemoglobin. Functions as a transporter that mediates the 1:1 exchange of inorganic anions across the erythrocyte membrane. Mediates chloride-bicarbonate exchange in the kidney, and is required for normal acidification of the urine. 1. Bruce, LJ. et al. (2000) The Biochemical journal 350 Pt 1, 41-51. PMID: 109268242. Rungroj, N. et al. (2004) The Journal of biological chemistry 279, 13833-8. PMID: 147345523. Schofield, AE. et al. (1992) Journal of molecular biology 223, 949-58. PMID: 15384054. Bruce, LJ. et al. (2005) Nature genetics 37, 1258-63. PMID: 162279985. Ungsupravate, D. et al. (2010) Molecular membrane biology 27, 92-103. PMID: 201518486. Shnitsar, V. et al. (2013) The Journal of biological chemistry 288, 33848-33860. PMID: 241215127. Genetet, S. et al. (2017) Scientific reports 7, 46170. PMID: 283873078. Vallese, F. et al. (2022) Nature structural & molecular biology 29, 706-718. PMID: 35835865 |
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| Note | For research use only. |
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