Anti-CD203c/ENPP3 Polyclonal Antibody (HT018014)

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规格：

50ug
100ug

数量：

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概述
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参考文献
产品说明书

HT018014

abinScience

种属反应性

Human

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human CD203c/ENPP3 (Met640-Pro857).

NPPase, PD-Ibeta, Phosphodiesterase I beta, PDNP3, CD203c, Ectonucleotide pyrophosphatase/phosphodiesterase family member 3, E-NPP 3, ENPP3, NPP3, Phosphodiesterase I/nucleotide pyrophosphatase 3, Nucleotide diphosphatase

Purified by antigen affinity column.

Accession号

O14638

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 (CD203c/ENPP3) is a ~100 kDa protein. Hydrolase that metabolizes extracellular nucleotides, including ATP, GTP, UTP and CTP. Also hydrolyzes extracellular 2',3'-cGAMP (cyclic GMP-AMP), a second messenger that activates TMEM173/STING and triggers type-I interferon production, and is therefore involved in the regulation of innate immune response. 2',3'-cGAMP appears to be further processed to GMP, AMP and inorganic phosphate. Limits mast cells and basophils response during inflammation and during the chronic phases of allergic responses by eliminating extracellular ATP, a signaling molecule activating these cells in an autocrine manner. Metabolizes extracellular ATP in the lumen of the small intestine, and thereby prevents ATP-induced apoptosis of intestinal plasmacytoid dendritic cells.

1. Gorelik, A. et al. (2018) The FEBS journal 285, 2481-2494. PMID: 29717535

2. Jin-Hua, P. et al. (1997) Genomics 45, 412-5. PMID: 9344668

3. Mardjuki, R. et al. (2024) Cell reports 43, 114209. PMID: 38749434

4. Vollmayer, P. et al. (2003) European journal of biochemistry 270, 2971-8. PMID: 12846830

5. Bühring, HJ. et al. (2001) Blood 97, 3303-5. PMID: 11342463

For research use only.

产品说明书

Anti-CD203c/ENPP3 Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

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试剂盒

实验相关试剂

Anti-CD203c/ENPP3 Polyclonal Antibody (HT018014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-CD203c/ENPP3 Polyclonal Antibody (HT018014)

概述

图片

参考文献

产品说明书

相关产品推荐

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