

| 货号 | HF663014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 种属反应性 | Human, Mouse, Rat | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human GLS (Ile221-Leu533). | ||||||||
| 靶标 | GLS1, Glutaminase kidney isoform, mitochondrial, KIAA0838, GLS, L-glutamine amidohydrolase, K-glutaminase | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | O94925 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Glutaminase kidney isoform, mitochondrial (GLS) is a ~73 kDa protein. Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate, the main excitatory neurotransmitter in the brain. 1. Rumping, L. et al. (2019) Human molecular genetics 28, 96-104. PMID: 30239721 2. Rumping, L. et al. (2019) JAMA neurology 76, 342-350. PMID: 30575854 3. van Kuilenburg, ABP. et al. (2019) The New England journal of medicine 380, 1433-1441. PMID: 30970188 | ||||||||
| Note | For research use only. |

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