Anti-KMO Polyclonal Antibody (HT083014)

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50ug
100ug

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概述
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参考文献
产品说明书

HT083014

abinScience

种属反应性

Human

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human KMO (Met1-Glu366).

KMO, Kynurenine 3-hydroxylase, Kynurenine 3-monooxygenase

Purified by antigen affinity column.

Accession号

O15229

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Kynurenine 3-monooxygenase (KMO) is a ~55 kDa protein. Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract (Probable).

1. Amaral, M. et al. (2013) Nature 496, 382-5. PMID: 23575632

2. Mole, DJ. et al. (2016) Nature medicine 22, 202-9. PMID: 26752518

3. Hutchinson, JP. et al. (2017) Nature communications 8, 15827. PMID: 28604669

4. Gao, J. et al. (2018) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 32, 2036-2045. PMID: 29208702

5. Kim, HT. et al. (2018) Cell chemical biology 25, 426-438.e4. PMID: 29429898

For research use only.

产品说明书

Anti-KMO Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-KMO Polyclonal Antibody (HT083014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-KMO Polyclonal Antibody (HT083014)

概述

图片

参考文献

产品说明书

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