Anti-FMO3 Polyclonal Antibody (HB603014)

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规格：

50ug
100ug

数量：

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概述
图片
参考文献
产品说明书

HB603014

abinScience

种属反应性

Human

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human FMO3 (Lys280-Thr532).

Dimethylaniline oxidase 3, FMO form 2, Dimethylaniline monooxygenase [N-oxide-forming] 3, FMO3, FMO II, FMO 3, Trimethylamine monooxygenase, Hepatic flavin-containing monooxygenase 3

Purified by antigen affinity column.

Accession号

P31513

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Flavin-containing monooxygenase 3 (FMO3) is a ~60 kDa protein. Essential hepatic enzyme that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including drugs as well as dietary compounds. Plays an important role in the metabolism of trimethylamine (TMA), via the production of trimethylamine N-oxide (TMAO) metabolite. TMA is generated by the action of gut microbiota using dietary precursors such as choline, choline containing compounds, betaine or L-carnitine. By regulating TMAO concentration, FMO3 directly impacts both platelet responsiveness and rate of thrombus formation.

1. Rawden, HC. et al. (2000) British journal of clinical pharmacology 49, 313-22. PMID: 10759686

2. Perez-Paramo, YX. et al. (2019) Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 28, 311-320. PMID: 30381441

3. Veeravalli, S. et al. (2020) Drug metabolism and disposition: the biological fate of chemicals 48, 378-385. PMID: 32156684

4. Lang, DH. et al. (1998) Biochemical pharmacology 56, 1005-12. PMID: 9776311

5. Zhu, W. et al. (2018) Journal of thrombosis and haemostasis : JTH 16, 1857-1872. PMID: 29981269

For research use only.

产品说明书

Anti-FMO3 Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

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Anti-FMO3 Polyclonal Antibody (HB603014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-FMO3 Polyclonal Antibody (HB603014)

概述

图片

参考文献

产品说明书

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