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Anti-ABCB9 Polyclonal Antibody (HV453014)

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概述
货号HV453014
品牌abinScience
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human ABCB9 (Val504-Ala766).
靶标ATP-binding cassette transporter 9, ABC transporter 9 protein, ATP-binding cassette sub-family B member 9, hABCB9, TAP-like protein, ABCB9, KIAA1520, TAPL
纯化方式Purified by antigen affinity column.
Accession号Q9NP78
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

ABC-type oligopeptide transporter ABCB9 is a ~84 kDa protein. ATP-dependent low-affinity peptide transporter which translocates a broad spectrum of peptides from the cytosol to the lysosomal lumen for degradation. Displays a broad peptide length specificity from 6-mer up to at least 59-mer peptides with an optimum of 23-mers. Binds and transports smaller and larger peptides with the same affinity. Favors positively charged, aromatic or hydrophobic residues in the N- and C-terminal positions whereas negatively charged residues as well as asparagine and methionine are not favored.

1. Wolters, JC. et al. (2005) The Journal of biological chemistry 280, 23631-6. PMID: 15863492
2. Demirel, O. et al. (2007) The Journal of biological chemistry 282, 37836-43. PMID: 17977821
3. Zhao, C. et al. (2008) The Journal of biological chemistry 283, 17083-91. PMID: 18434309
4. Demirel, Ö. et al. (2012) Journal of cell science 125, 4230-40. PMID: 22641697
5. Zollmann, T. et al. (2015) Proceedings of the National Academy of Sciences of the United States of America 112, 2046-51. PMID: 25646430
6. Bock, C. et al. (2018) Scientific reports 8, 15662. PMID: 30353140
7. Graab, P. et al. (2019) The Journal of biological chemistry 294, 7308-7323. PMID: 30877195
8. Bock, C. et al. (2019) Scientific reports 9, 11884. PMID: 31417173
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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