Anti-NCF1 Polyclonal Antibody (HB843014)

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规格：

50ug
100ug

数量：

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概述
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参考文献
产品说明书

HB843014

abinScience

种属反应性

Human

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human NCF1 (Met1-Val390).

SH3PXD1A, NCF1, p47-phox, 47 kDa autosomal chronic granulomatous disease protein, Nox-organizing protein 2, NOXO2, SH3 and PX domain-containing protein 1A, NCF-1, 47 kDa neutrophil oxidase factor, NCF-47K, Nox organizer 2, Neutrophil NADPH oxidase factor 1, Neutrophil cytosol factor 1

Purified by antigen affinity column.

Accession号

P14598

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Neutrophil cytosol factor 1 (NCF1) is a ~44 kDa protein. Subunit of the phagocyte NADPH oxidase complex that mediates the transfer of electrons from cytosolic NADPH to O2 to produce the superoxide anion (O2(-)). In the activated complex, electrons are first transferred from NADPH to flavin adenine dinucleotide (FAD) and subsequently transferred via two heme molecules to molecular oxygen, producing superoxide through an outer-sphere reaction. Activation of the NADPH oxidase complex is initiated by the assembly of cytosolic subunits of the NADPH oxidase complex with the core NADPH oxidase complex to form a complex at the plasma membrane or phagosomal membrane. This activation process is initiated by phosphorylation dependent binding of the cytosolic NCF1/p47-phox subunit to the C-terminus of CYBA/p22-phox.

1. Lomax, KJ. et al. (1989) Science (New York, N.Y.) 245, 409-12. PMID: 2547247

2. Volpp, BD. et al. (1989) Proceedings of the National Academy of Sciences of the United States of America 86, 7195-9. PMID: 2550933

3. Liu, X. et al. (2024) Nature 627, 189-195. PMID: 38355798

4. Groemping, Y. et al. (2003) Cell 113, 343-55. PMID: 12732142

5. Kilpatrick, LE. et al. (2010) Journal of leukocyte biology 87, 153-64. PMID: 19801500

For research use only.

产品说明书

Anti-NCF1 Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

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试剂盒

实验相关试剂

Anti-NCF1 Polyclonal Antibody (HB843014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-NCF1 Polyclonal Antibody (HB843014)

概述

图片

参考文献

产品说明书

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