Anti-USP14 Polyclonal Antibody (HX186014)

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规格：

50ug
100ug

数量：

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概述
图片
参考文献
产品说明书

HX186014

abinScience

种属反应性

Human, Mouse

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human USP14 (Met1-Gln494).

Deubiquitinating enzyme 14, TGT, Ubiquitin thioesterase 14, Ubiquitin carboxyl-terminal hydrolase 14, Ubiquitin-specific-processing protease 14, USP14

Purified by antigen affinity column.

Accession号

P54578

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Ubiquitin carboxyl-terminal hydrolase 14 (USP14) is a ~56 kDa protein. Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Also serves as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1.

1. Liu, D. et al. (2022) Proceedings of the National Academy of Sciences of the United States of America 119. PMID: 35145029

2. Koulich, E. et al. (2008) Molecular biology of the cell 19, 1072-82. PMID: 18162577

3. Kuo, CL. et al. (2017) Proceedings of the National Academy of Sciences of the United States of America 114, E3404-E3413. PMID: 28396413

4. Mines, MA. et al. (2009) The Journal of biological chemistry 284, 5742-52. PMID: 19106094

5. Nagai, A. et al. (2009) Biochemical and biophysical research communications 379, 995-1000. PMID: 19135427

6. Chen, M. et al. (2016) Molecular cell 64, 105-119. PMID: 27666593

For research use only.

产品说明书

Anti-USP14 Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-USP14 Polyclonal Antibody (HX186014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-USP14 Polyclonal Antibody (HX186014)

概述

图片

参考文献

产品说明书

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