Anti-ALDOB Polyclonal Antibody (HY240014)

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50ug
100ug

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HY240014

abinScience

种属反应性

Human, Mouse, Rat

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human ALDOB (Thr9-Tyr364).

ALDOB, Liver-type aldolase, Fructose-bisphosphate aldolase B, ALDB

Purified by antigen affinity column.

Accession号

P05062

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fructose-bisphosphate aldolase B (ALDOB) is a ~39 kDa protein. Catalyzes the aldol cleavage of fructose 1,6-biphosphate to form two triosephosphates dihydroxyacetone phosphate and D-glyceraldehyde 3-phosphate in glycolysis as well as the reverse stereospecific aldol addition reaction in gluconeogenesis. In fructolysis, metabolizes fructose 1-phosphate derived from the phosphorylation of dietary fructose by fructokinase into dihydroxyacetone phosphate and D-glyceraldehyde. Acts as an adapter independently of its enzymatic activity, exerts a tumor suppressor role by stabilizing the ternary complex with G6PD and TP53 to inhibit G6PD activity and keep oxidative pentose phosphate metabolism in check.

1. Santamaria, R. et al. (2000) The Biochemical journal 350 Pt 3, 823-8. PMID: 10970798

2. Sánchez-Gutiérrez, JC. et al. (2002) Journal of medical genetics 39, e56. PMID: 12205126

3. Esposito, G. et al. (2010) Human mutation 31, 1294-303. PMID: 20848650

4. Li, M. et al. (2020) Nature cancer 1, 735-747. PMID: 35122041

For research use only.

产品说明书

Anti-ALDOB Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-ALDOB Polyclonal Antibody (HY240014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-ALDOB Polyclonal Antibody (HY240014)

概述

图片

参考文献

产品说明书

相关产品推荐

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