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Anti-CNDP2 Polyclonal Antibody (HV578014)

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概述
货号HV578014
品牌abinScience
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human CNDP2 (Val269-Asp475).
靶标Peptidase A, PEPA, CNDP2, Carnosine dipeptidase II, CN2, Epididymis secretory protein Li 13, Glutamate carboxypeptidase-like protein 1, CNDP dipeptidase 2, HEL-S-13, Cytosolic non-specific dipeptidase, CPGL
纯化方式Purified by antigen affinity column.
Accession号Q96KP4
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Cytosolic non-specific dipeptidase (CNDP2) is a ~52 kDa protein. Catalyzes the peptide bond hydrolysis in dipeptides, displaying a non-redundant activity toward threonyl dipeptides. Mediates threonyl dipeptide catabolism in a tissue-specific way. Has high dipeptidase activity toward cysteinylglycine, an intermediate metabolite in glutathione metabolism. Metabolizes N-lactoyl-amino acids, both through hydrolysis to form lactic acid and amino acids, as well as through their formation by reverse proteolysis. Plays a role in the regulation of cell cycle arrest and apoptosis.

1. Teufel, M. et al. (2003) The Journal of biological chemistry 278, 6521-31. PMID: 12473676
2. Kaur, H. et al. (2009) The Journal of biological chemistry 284, 14493-502. PMID: 19346245
3. Jansen, RS. et al. (2015) Proceedings of the National Academy of Sciences of the United States of America 112, 6601-6. PMID: 25964343
4. Zhang, P. et al. (2006) Clinical cancer research : an official journal of the American Association for Cancer Research 12, 6617-25. PMID: 17121880
5. Zhang, Z. et al. (2014) Molecular medicine (Cambridge, Mass.) 20, 17-28. PMID: 24395568
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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