

| 货号 | HV615014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human CCL17/TARC (Ala24-Ser94). | ||||||||
| 靶标 | Thymus and activation-regulated chemokine, SCYA17, TARC, Small-inducible cytokine A17, C-C motif chemokine 17, CC chemokine TARC, CCL17 | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q92583 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | C-C motif chemokine 17 (CCL17/TARC) is a ~10 kDa protein. Chemokine, which displays chemotactic activity for T lymphocytes, preferentially Th2 cells, but not monocytes or granulocytes. Therefore plays an important role in a wide range of inflammatory and immunological processes. Acts by binding to CCR4 at T-cell surface. Mediates GM-CSF/CSF2-driven pain and inflammation. In the brain, required to maintain the typical, highly branched morphology of hippocampal microglia under homeostatic conditions. 1. Imai, T. et al. (1996) The Journal of biological chemistry 271, 21514-21. PMID: 8702936 2. Imai, T. et al. (1997) The Journal of biological chemistry 272, 15036-42. PMID: 9169480 3. Garlisi, CG. et al. (1999) European journal of immunology 29, 3210-5. PMID: 10540332 4. Achuthan, A. et al. (2016) The Journal of clinical investigation 126, 3453-66. PMID: 27525438 | ||||||||
| Note | For research use only. |

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