

| 货号 | HT236014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human CES2 (His452-Leu559). | ||||||||
| 靶标 | Cocaine esterase, CES2, Carboxylesterase 2, CE-2, ICE, Methylumbelliferyl-acetate deacetylase 2, hCE-2 | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | O00748 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Cocaine esterase (CES2) is a ~61 kDa protein. Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows high catalytic efficiency for hydrolysis of cocaine, 4-methylumbelliferyl acetate, heroin and 6-monoacetylmorphine. Hydrolyzes aspirin, substrates with large alcohol group and small acyl group and endogenous lipids such as triacylglycerol. Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes of 2-arachidonoylglycerol and prostaglandins. 1. Pindel, EV. et al. (1997) The Journal of biological chemistry 272, 14769-75. PMID: 9169443 2. Lian, J. et al. (2018) Protein & cell 9, 178-195. PMID: 28677105 3. Xie, S. et al. (2010) Chemical research in toxicology 23, 1890-904. PMID: 21049984 | ||||||||
| Note | For research use only. |

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