

| 货号 | HY371014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human GLI1 (Phe2-Glu234). | ||||||||
| 靶标 | Oncogene GLI, GLI, Glioma-associated oncogene, GLI1, Zinc finger protein GLI1 | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P08151 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Zinc finger protein GLI1 is a ~117 kDa protein. Acts as a transcriptional activator. Binds to the DNA consensus sequence 5'-GACCACCCA-3'. Regulates the transcription of specific genes during normal development. Plays a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling. 1. Murone, M. et al. (2000) Nature cell biology 2, 310-2. PMID: 10806483 2. Lo, HW. et al. (2009) Cancer research 69, 6790-8. PMID: 19706761 3. Maloverjan, A. et al. (2010) Experimental cell research 316, 627-37. PMID: 19878745 4. Gilder, AS. et al. (2013) Biochemical and biophysical research communications 440, 431-6. PMID: 24076122 5. Zhang, Y. et al. (2013) Nature communications 4, 2608. PMID: 24217340 6. Cherry, AL. et al. (2013) Acta crystallographica. Section D, Biological crystallography 69, 2563-79. PMID: 24311597 7. Kinzler, KW. et al. (1990) Molecular and cellular biology 10, 634-42. PMID: 2105456 8. Pavletich, NP. et al. (1993) Science (New York, N.Y.) 261, 1701-7. PMID: 8378770 | ||||||||
| Note | For research use only. |

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