Anti-SCNN1A Polyclonal Antibody (HW302014)

价格:

规格：

50ug
100ug

数量：

一键复制产品信息

概述
图片
参考文献
产品说明书

HW302014

abinScience

种属反应性

Human

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human SCNN1A (Tyr112-Thr543).

ENaCA, SCNN1A, Epithelial Na(+) channel subunit alpha, SCNEA, SCNN1, Alpha-NaCH, Amiloride-sensitive sodium channel subunit alpha, Nonvoltage-gated sodium channel 1 subunit alpha, Alpha-ENaC

Purified by antigen affinity column.

Accession号

P37088

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Epithelial sodium channel subunit alpha (SCNN1A/SCNN1) is a ~75 kDa protein. This is one of the three pore-forming subunits of the heterotrimeric epithelial sodium channel (ENaC), a critical regulator of sodium balance and fluid homeostasis. ENaC operates in epithelial tissues, where it mediates the electrodiffusion of sodium ions from extracellular fluid through the apical membrane of cells, with water following osmotically. It plays a key role in maintaining sodium homeostasis through electrogenic sodium reabsorption in the kidneys. Additionally, ENaC is essential for airway surface liquid homeostasis, which is crucial for proper mucus clearance.

1. Noreng, S. et al. (2018) eLife 7. PMID: 30251954

2. Noreng, S. et al. (2020) eLife 9. PMID: 32729833

3. McDonald, FJ. et al. (1994) The American journal of physiology 266, L728-34. PMID: 8023962

4. Voilley, N. et al. (1994) Proceedings of the National Academy of Sciences of the United States of America 91, 247-51. PMID: 8278374

5. Goulet, CC. et al. (1998) The Journal of biological chemistry 273, 30012-7. PMID: 9792722

6. Hobbs, CA. et al. (2013) American journal of physiology. Lung cellular and molecular physiology 305, L990-L1001. PMID: 24124190

7. Salih, M. et al. (2017) Journal of the American Society of Nephrology : JASN 28, 3291-3299. PMID: 28710092

8. Saxena, A. et al. (2002) The Journal of clinical endocrinology and metabolism 87, 3344-50. PMID: 12107247

For research use only.

产品说明书

Anti-SCNN1A Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-SCNN1A Polyclonal Antibody (HW302014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-SCNN1A Polyclonal Antibody (HW302014)

概述

图片

参考文献

产品说明书

相关产品推荐

获取报价