Anti-FCN1 Polyclonal Antibody (HT184014)

价格:

规格：

50ug
100ug

数量：

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概述
图片
参考文献
产品说明书

HT184014

abinScience

种属反应性

Human

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human FCN1 (Gly130-Ala326).

Ficolin-alpha, FCNM, Ficolin-A, FCN1, Ficolin-1, Collagen/fibrinogen domain-containing protein 1, M-ficolin

Purified by antigen affinity column.

Accession号

O00602

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Ficolin-1 (FCN1) is a ~35 kDa protein. Extracellular lectin, which acts as a pattern recognition receptor that initiates the lectin pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. Specifically recognizes and binds carbohydrates on the pathogen surface, activating the MASP1 serine protease and initiating the proteolytic cascade of the lectin complement pathway. Binds preferentially to 9-O-acetylated 2-6-linked sialic acid derivatives and to various glycans containing sialic acid engaged in a 2-3 linkage. May also activate monocytes through a G protein-coupled receptor, FFAR2, inducing the secretion of interleukin-8/IL-8.

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1. Liu, Y. et al. (2005) Journal of immunology (Baltimore, Md. : 1950) 175, 3150-6. PMID: 16116205

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2. Garlatti, V. et al. (2007) The Journal of biological chemistry 282, 35814-20. PMID: 17897951

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3. Gout, E. et al. (2010) The Journal of biological chemistry 285, 6612-22. PMID: 20032467

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4. Honoré, C. et al. (2010) Journal of leukocyte biology 88, 145-58. PMID: 20400674

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5. Zhang, J. et al. (2010) Journal of immunology (Baltimore, Md. : 1950) 185, 6899-910. PMID: 21037097

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For research use only.

Western blot

Western blot analysis was performed using anti-FCN1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse liver lysate
Lane 2: Rat liver lysate

产品说明书

Anti-FCN1 Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-FCN1 Polyclonal Antibody (HT184014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-FCN1 Polyclonal Antibody (HT184014)

概述

图片

参考文献

产品说明书

相关产品推荐

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