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Anti-Human FCN3 Polyclonal Antibody (HF819014)

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概述
货号HF819014
品牌abinScience
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human FCN3 (Glu34-Met297).
靶标Hakata antigen, HAKA1, FCN3, Collagen/fibrinogen domain-containing lectin 3 p35, FCNH, Ficolin-3, Collagen/fibrinogen domain-containing protein 3
纯化方式Purified by antigen affinity column.
Accession号O75636
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Ficolin-3 (FCN3) is a ~32 kDa protein. Calcium-dependent lectin, which acts as a pattern recognition receptor that initiates the lectin pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. Specifically recognizes and binds carbohydrates on the pathogen surface, activating the MASP1 serine protease and initiating the proteolytic cascade of the lectin complement pathway. Specifically binds N-Acetylglucosamine (GlcNAc,) GalNAc (N-acetylgalactosamine) and D-fucose on the surface of pathogens, as well as mono/oligosaccharide and lipopolysaccharides from S.typhimurium and S.minnesota.

1. Matsushita, M. et al. (2002) Journal of immunology (Baltimore, Md. : 1950) 168, 3502-6. PMID: 11907111
2. Kuraya, M. et al. (2005) Immunobiology 209, 689-97. PMID: 15804047
3. Garlatti, V. et al. (2007) The EMBO journal 26, 623-33. PMID: 17215869
4. Bidula, S. et al. (2015) Immunology 146, 281-91. PMID: 26133042
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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