Anti-Human LBR Polyclonal Antibody (HC667014)

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规格：

50ug
100ug

数量：

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概述
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参考文献
产品说明书

HC667014

abinScience

种属反应性

Human, Rat

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human LBR (Ala7-Arg61).

LMN2R, LBR, C14SR, Integral nuclear envelope inner membrane protein, Sterol C14-reductase, 3-beta-hydroxysterol Delta (14)-reductase, Delta(14)-sterol reductase LBR, Lamin-B receptor, Delta-14-SR, C-14 sterol reductase

Purified by antigen affinity column.

Accession号

Q14739

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Delta(14)-sterol reductase LBR is a ~70 kDa protein. Catalyzes the reduction of the C14-unsaturated bond of lanosterol, as part of the metabolic pathway leading to cholesterol biosynthesis. Plays a critical role in myeloid cell cholesterol biosynthesis which is essential to both myeloid cell growth and functional maturation. Mediates the activation of NADPH oxidases, perhaps by maintaining critical levels of cholesterol required for membrane lipid raft formation during neutrophil differentiation. Anchors the lamina and the heterochromatin to the inner nuclear membrane.

1. Waterham, HR. et al. (2003) American journal of human genetics 72, 1013-7. PMID: 12618959

2. Bennati, AM. et al. (2006) Biochimica et biophysica acta 1761, 677-85. PMID: 16784888

3. Clayton, P. et al. (2010) Nucleus (Austin, Tex.) 1, 354-66. PMID: 21327084

4. Tsai, PL. et al. (2016) eLife 5. PMID: 27336722

5. Silve, S. et al. (1998) Biochimica et biophysica acta 1392, 233-44. PMID: 9630650

6. Duband-Goulet, I. et al. (2000) Biochemistry 39, 6483-8. PMID: 10828963

For research use only.

产品说明书

Anti-Human LBR Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

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试剂盒

实验相关试剂

Anti-Human LBR Polyclonal Antibody (HC667014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human LBR Polyclonal Antibody (HC667014)

概述

图片

参考文献

产品说明书

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