Anti-GREM1 Polyclonal Antibody (HT246014)

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概述
图片
参考文献
产品说明书

概述

货号

HT246014

品牌

abinScience

描述

Anti-GREM1 Polyclonal Antibody (HT246014) is a rabbit polyclonal antibody detecting GREM1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Chicken, and Macaca mulatta.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human GREM1 (Lys26-Asp184).

靶标

Cysteine knot superfamily 1, BMP antagonist 1, CKTSF1B1, Down-regulated in Mos-transformed cells protein, Increased in high glucose protein 2, IHG-2, DRM, GREM1, Gremlin-1, Cell proliferation-inducing gene 2 protein, DAN domain family member 2, DAND2

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

O60565

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Gremlin-1 (GREM1/DAND2) is a ~20 kDa protein. Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as a BMP antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. Down-regulates the BMP4 signaling in a dose-dependent manner. Antagonist of BMP2; inhibits BMP2-mediated differentiation of osteoblasts (in vitro). Acts as inhibitor of monocyte chemotaxis. Can inhibit the growth or viability of normal cells but not transformed cells when is overexpressed.

1. Kišonaitė, M. et al. (2016) The Biochemical journal 473, 1593-604. PMID: 27036124

Note

For research use only.

图片

参考文献

产品说明书

Anti-GREM1 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-GREM1 Polyclonal Antibody (HT246014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-GREM1 Polyclonal Antibody (HT246014)

概述

图片

参考文献

产品说明书

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