Anti-Human GSDMB Polyclonal Antibody (HP757014)

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100ug

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参考文献
产品说明书

HP757014

abinScience

种属反应性

Human

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human GSDMB (Pro200-Ser411).

GSDML, p16, GSDMB-NT, GSDMB-CT, Gasdermin-like protein, GSDMB, p30, Gasdermin-B

Purified by antigen affinity column.

Accession号

Q8TAX9

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Gasdermin-B (GSDMB) is a ~47 kDa protein. Precursor of a pore-forming protein that acts as a downstream mediator of granzyme-mediated cell death. This form constitutes the precursor of the pore-forming protein: upon cleavage, the released N-terminal moiety (Gasdermin-B, N-terminal) binds to membranes and forms pores, triggering pyroptosis. Also acts as a regulator of epithelial cell repair independently of programmed cell death: translocates to the plasma membrane and promotes epithelial maintenance and repair by regulating PTK2/FAK-mediated phosphorylation of PDGFA.

1. Zhou, Z. et al. (2020) Science (New York, N.Y.) 368. PMID: 32299851

2. Rana, N. et al. (2022) Cell 185, 283-298.e17. PMID: 35021065

For research use only.

产品说明书

Anti-Human GSDMB Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human GSDMB Polyclonal Antibody (HP757014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human GSDMB Polyclonal Antibody (HP757014)

概述

图片

参考文献

产品说明书

相关产品推荐

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